Day 6: lepto, bucella, anthrax, scrub typhus
Today’s lectures started with a breakdown of leptospirosis, I think the take away message is that this can look like a vasculitis (in a sense it is – invading endothelial cells), much like Rickettsia diseases. It can enter the body through mucosa, skin cuts/abrasions and the organism has burrowing motility. Just about any organ is fair game – liver, CNS, kidneys, and lungs. The organism is often transmitted from rodents, and can stay in rat kidneys for years. The bacteria can survive in fresh water and soil for many weeks, especially with neutral or alkaline pH, thus people at risk are sewage workers, people that work on rice farms, soldiers, people going rafting, and triathalon-ers. Rodents are the reservoir but there are over 150 animal reservoirs including cattle, pigs, and dogs. Thus it being labelled as the champion of zoonoses. The study above was done in India at several hospitals, the above are a list of undifferentiated fever of people presenting, notic...
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